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Assessment of Phenylboronic Acid Nitrogen Mustards as Potent and Selective Drug Candidates for Triple-Negative Breast Cancer
Heli Fan, Muhammad Asad Uz Zaman, Wenbing Chen, Taufeeque Ali, Anahit Campbell, Qi Zhang, Nurul Islam Setu, Eron Saxon, Nicolas M Zahn, Anna M Benko, Leggy A Arnold, Xiaohua Peng
ACS Pharmacology & Translational Science 2021 |
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Design and evaluation of heterobivalent PAR1–PAR2 ligands as antagonists of calcium mobilization
Mark Majewski, Disha Gandhi, Ricardo Rosas, Revathi Kodali, Leggy A Arnold, Chris Dockendorff
ACS Medicinal Chemistry Letters 2018, 10(1), 121-126. |
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Discovery and Optimization of Novel Hydrogen Peroxide Activated
Wenbing Chen, Heli Fan, Kumudha Balakrishnan, Yibin Wang, Huabing Sun, Yukai Fan, Varsha Gandhi, Leggy A. Arnold, and Xiaohua Peng*
Journal of Medicinal Chemistry 2018, 61, 9132-9145. |
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Hydrogen Peroxide Activated Quinone Methide Precursors with Enhanced DNA Cross-Linking Capability and Cytotoxicity towards Cancer Cells
Yibin Wang, Heli Fan, Kumudha Balakrishnan, Zechao Lin, Sheng Cao, Wenbing Chen, Yukai Fan, Quibria A. Guthrie, Huabing Sun, Kelly A. Teske, Varsha Gandhib, Leggy A. Arnold, Xiaohua Peng*
European Journal of Medicinal Chemistry 2017, 133, 197-207. |
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Antitumor activity of 3-Indolylmethanamines 31B and PS121912
Margaret L Guthrie, Preetpal S. Sidhu, Emily K. Hill, Timothy C. Horan, Premchendar Nandhikonda, Kelly Teske, Nina Y. Yuan, Marino Sidorko, Revathi Kodali, James M. Cook, Lanlan Han, Nicholas R. Silvaggi, Daniel D. Bikle, Richard G. Moore, Rakesh K. Singh, and Leggy A. Arnold*
Anticancer Res. 2015, 35(11), 6001-6007. |
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Anticancer Activity of VDR-Coregulator Inhibitor PS121912
Preetpal S. Sidhu, Kelly Teske, Belaynesh Feleke, Nina Y. Yuan, Margaret L. Guthrie, Grant B. Fernstrum, Nishita D. Vyas, Lanlan Han, Joshua Preston, Jonathan W. Bogart, Nicholas R. Silvaggi, James M. Cook, Rakesh K. Singh, Daniel D. Bikle, Leggy A. Arnold*
Cancer Chemotherapy and Pharmacology 2014, 74(4), 787-798. |
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PT19c, Another Nonhypercalcemic Vitamin D2 Derivative, Demonstrates Antitumor Efficacy in Epithelial Ovarian and Endometrial Cancer Models
Nada Kawar, Shannon Maclaughlan, Timothy C. Horan, Alper Uzun, Thilo S. Lange, Kyu K. Kim, Russell Hopson, Ajay P. Singh, Preetpal S. Sidhu, Kyle A. Glass, Sunil Shaw, James F. Padbury, Nicholi Vorsa, Leggy A. Arnold, Richard G. Moore, Laurent Brard, Rakesh K. Singh
Genes & Cancer 2013, 4(11-12), 524-534. |
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Efficacy of a Non-Hypercalcemic Vitamin-D2 Derived Anti-Cancer Agent (MT19c) and Inhibition of Fatty Acid Synthesis in an Ovarian Cancer Xenograft Model
Richard G. Moore, Thilo S. Lange, Katina Robinson, Kyu K. Kim, Alper Uzun, Timothy C. Horan, Nada Kawar, Naohiro Yano, Sharon R. Chu, Quanfu Mao, Laurent Brard, Monique E. DePaepe, James F. Padbury, Leggy A. Arnold, Alexander Brodsky, Tun-Li Shen, Rakesh K. Singh*
PLOS one 2012, 7, e34443.
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Evaluation of the first Ergocalciferol-derived, non hypercalcemic anti-cancer agent MT19c in ovarian cancer SKOV-3 cell lines
Laurent Brard, Thilo S. Lange, Katina Robison, Kyu Kwang Kim, Tahniyath Ara, Megan Marie McCallum, Leggy A. Arnold, Richard G. Moore, Rakesh K. Singh*
Gynecologic Oncology, 2011, 123(2), 370-8
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An Integrated In Vitro and In Vivo High-Throughput Screen Identifies Treatment Leads for Ependymoma
Jennifer M. Atkinson, Anang A. Shelat, Angel Montero Carcaboso, Tanya A. Kranenburg, Leggy A. Arnold, Nidal Boulos, Karen Wright, Robert A. Johnson, Helen Poppleton, Kumarasamypet M. Mohankumar, Clementine Féau, Timothy Phoenix, Paul Gibson, Liqin Zhu, Yiai Tong, Chris Eden, David W. Ellison, Waldemar Priebe, Dimpy Koul, W. K. Alfred Yung, Amar Gajjar, Clinton F. Stewart, R. Kiplin Guy, Richard J. Gilbertson*
Cancer Cell, 2011, 20 (3), 384-399. |
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Identification and Characterization of the First Small Molecule Inhibitor of MDMX
Damon Reed, Ying Shen, Anang A. Shelat, Leggy A. Arnold, Antonio M. Ferreira, Fangyi Zhu, Nicholas Mills, David C. Smithson, Catherine A. Regni, Donald Bashford, Samantha A. Cicero, Brenda A. Schulman, Aart G. Jochemsen, R. Kiplin Guy, and Michael A. Dyer*
J. Biol. Chem. 2010, 285, 10786-96.
*corresponding authors |
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