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Overview

We are an academic research laboratory in field of chemical biology in the Department of Chemistry and Biochemistry at the University of Wisconsin -Milwaukee.

Our research is focused on two primary targets: 1) the vitamin D receptor and 2) the GABA (A) receptors.

Our approach is to develop small molecules as can function as molecular probes in complex biological systems and new drug candidates for diseases mediated by the two primary targets mentioned above.

We are combining many areas of science including medicinal chemistry, biochemistry, molecular biology, (bio)analytical chemistry, high throughput screening, assay development, virtual screening, molecular docking and pharmacological profiling.

News

Postdoctoral Researcher Interview: PreetPal Singh Sidu (Department of Medicinal Chemistry and Institute for Structural Biology and Drug Discovery
Virginia Commonwealth University, Richmond, VA) - Designing Allosteric Inhibitors of Thombin, Wednesday June 27th, 2012, 2:00pm.

Publication in Journal of Medicinal Chemistry: Discovery of the First Irreversible Small Molecule Inhibitors of the Interaction between the Vitamin D Receptor and Coactivators

University of Wisconsin-Milwaukee Department of Chemistry and Biochemistry-Arnold Group Chemistry Building 3210 Cramer Street Milwaukee, WI 53211-3029